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Polymeric (nano)materials – from construct to medical use

Group leader: prof.Ing. Jiří Brožek, CSc.(ORCID: 0000-0001-5126-3626)

Group members:

Ing. Václava Benešová
Ing. Lenka Malinová, Ph.D.(ORCID: 0000-0002-5266-8833)
Ing. Lucie Reinišová (ORCID: 0000-0002-6284-6103)
prof.Ing. Jan Roda, CSc.
prof.Ing. Petr Sysel, CSc.(ORCID: 0000-0002-8661-4905)

Research activities

ADVANCED POLYMERIC MATERIALS AND (NANO)COMPOSITES

  • Synthesis of polymers based on polyimides, polyamides, polyesteramides, polyesters, poly(propyleneglycol fumarate)
  • Using different techniques for preparation of (nano)composites – polymerization with in situ intercalation, melt mixing, from dispersion polymer/solution, unconventional methods
  • Exploration of the influence of the additives - silica, metal organic frameworks, magnetic particles, layered silicate, double hydroxide, graphene(oxide) - on properties of the products

 ◳ Obrázek1 (png) → (originál)

  • Application: construction materials, polymer flammability retarders, polymeric membranes and barriers, bone cement in surgery

    Selected publications:
  • Minář J., Doležal P., Brožek J.: The effect of nanocomposite synthesis and the drying procedure of graphene oxide dispersion on the polycaprolactone/graphene oxide nanocomposite properties, Polymers and Polymer Composites, 2022, 30, 1.
  • Janegová K., Sysel P., Kulhánková H., Perfilov V.A., Bernauer M., Fíla V.: Poly(imide-siloxane) films with controlled thickness. Journal of Applied Polymer Science 2021, 138, e49893.
  • Sysel P., Kulhánková H., Weinertová K.: Polyimides prepared without the use of toxic amidic solvents. Journal of Polymer Research 2020, 27, 227.
  • Minář J., Brožek J., Michalcová A., Hadravová R., Slepička P.: Functionalization of graphene oxide with poly(ε-caprolactone) for enhanced interfacial adhesion in polyamide 6 nanocomposites. Composites Part B: Engineering 2019, 174, 107019.
  • Diblíková P., Sysel P., Čapek P.: Mixed-matrix membranes based on 6FDA-ODA polyimide and silicalite 1 with homogeneous spatial distribution of particles.  Polymer 2019, 178, 121576.

(NANO)FIBER LAYERS

  • Synthesis of materials based on polyamides, polyesteramides or biodegradable polyesters suitable for preparation of nanofibers, microfibers and porous microfibers
  • Using different technics for preparation of fibers - electrospinning from solutions and melt, melt-blown (in cooperation with Technical University Liberec)                                                                         
     ◳ Obrázek2 (png) → (originál) 
  • Degradation testing of fibers made from biodegradable materials in different media - abiotic hydrolysis (model), in enzymes, compost or sewage sludge                                                                        
     ◳ Obrázek3 (png) → (originál) 
  • Testing their cytotoxicity, biocompatibility or cell proliferation on fiber layers (in cooperation with Institute of Experimental Medicine CAS)
  • Application: in filtration technologies, sorbents, scaffolds in (bone) tissue engineering

    Selected publications:
  • Holec P., Jirkovec R., Kalous T., Baťka O., Brožek J., Chvojka J.: The Potential for the Direct and Alternating Current-Driven Electrospinning of Polyamides, Nanomaterials 2022, 12, 665.
  • Blažková L., Malinová L., Benešová V., Roda J., Brožek J.: Nanofibers prepared by electrospinning from solutions of biobased polyamide 4. Journal of Polymer Science, Part A: Polymer Chemistry 2017, 55(13), 2203.

(NANO)PARTICLES

  • Synthesis and complex characterization of polyestercarbonates for biomedical devices
  • Preparation of lipid-polymer hybrid nanoparticle systems for cancer therapy 

 ◳ Obrázek4 (png) → (originál)

Collaboration with:

  • Companies: PolyPLASTY s.r.o., SINTEX a.s., ELMARCO s.r.o., Průša research a.s., PRAKAB s.r.o.
  • Institutions: Department of Water Technology and Environmental Engineering, UCT Prague; Institute of Experimental Medicine CAS; Department of Nonwovens and Nanofibrous Materials,Technical University Liberec, Institute of Molecular Genetics CAS


If you are interested in research work in our laboratories, please contact:
Prof. Jiří Brožek, room B124, +420 220 443 190; jiri.brozek@vscht.cz
Prof. Petr Sysel, room B129, +420 220 443 196; petr.sysel@vscht.cz
Ing. Lucie Reinišová, room B126, +420 220 443 192; lucie.reinisova@vscht.cz

Updated: 4.5.2022 08:53, Author: Jan Merna

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Copyright: UCT Prague 2015
Information provided by the Department of International Relations and the Department of R&D. Technical support by the Computing Centre.
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